Medical Neuroscience Seminar_Varna-to-Kanazawa-to-Varna…and back again: a primate neurogenesis journey

Event Details

【Theme】Varna-to-Kanazawa-to-Varna…and back again: a primate neurogenesis journey
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【Speaker】Prof. Anton B. Tonchev, Medical University-Varna, Bulgaria

The brain has the ability of continuous neuronal production, in some of its regions. The reason for this is that these regions, called “stem cell niches”, retain neural stem cells (NSCs) throughout life. The NSCs may produce neurons and glia in one such zone or only glia in another zone, due to a differential gene expression. Some 26 years ago I arrived for the first time in Kanazawa from Varna, Bulgaria, and we began studying how the NSCs operate in the adult monkey brain. This scientific journey led on to Europe, and back to Kanazawa, and still goes on. We identified how expression of different genetic programs (coding and non-coding transcripts) in two rostro-caudal domains of the macaque subventricular zone (SVZ) may relate to their differential neurogenic potential. The talk will discuss the neuroanatomy of neurogenesis in the adult monkey brain and how brain ischemia can become a tool to study the neurogenic potential of the stem cell domains.

【A course eligible for credit】
●Division of Medicine (Doctoral Course), Graduate School of Medical Sciences
Course name: "Up-to-date Seminar"

● School of Medicine
Course Title "Latest Medical Research"

Contact

Kanazawa University Faculty of Medicine Department of Neurology Hiroshi Kawasaki kawasaki-labo@umin.ac.jp